Using Drugs To Combat Hair Loss

If you are thinking about treating hair loss with medication here’s a few scary facts about your favorite prescribed drugs.





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Propecia is an infamous drug manufactured by Merck to combat hair loss. However this hair loss drug ended with expensive law suits after it triggered a variety of negative effects, consisting of long-term sexual disorders.

In 1997, pharmaceutical monolith Merck & Co unveiled Propecia as a brand-new use for finasteride, an artificial compound substance the business established 5 years earlier. Initially marketed as Proscar, physicians initially recommended 5 mg of finasteride to deal with benign prostatic hyperplasia (BPH), more typically referred to as an enlarged prostate gland.

Like minoxidil it was discovered that the Proscar treatment produced exceptional adverse effects in the manner than some clients began to grow hair. By dropping the dosage of finasteride to 1 mg, scientists discovered a method to remedy male pattern hair loss, a genetic condition that influences near HALF of the male population aged 50 an over.


Hair Loss Drug Propecia In Clinical Trials

With almost half a billion dollars of study behind it, Propecia went into the drug market with grand plans. After its very first year, around 400,000 males in the United States were being prescribed Propecia and ingesting the drug on a daily dosage.

Merck listed possible sexual side effects can occur after taking Propecia and Proscar and the initial scientific trials noticed some adverse effects. It seemed that the scientists conducting these tests did not revel the true extent of the effects to Merck’s Directors.

 

A High Percentage Of Users Noticed Bad Effects

Upon approval of the drug, Merck divulged that 3.8 percent of Propecia clients had several unfavorable sexual experiences, compared to 2.1 percent of clients taking a placebo. Exactly what it failed to discuss with the scientists conducting the clinical trials, nevertheless, was that these issues can continue even after clients stop taking the drug. Merck initially asserted that all of these concerns would rectify after discontinuation of the drug.

Propecia and Proscar come from a course of drugs called 5-alpha-reductase inhibitors, which are made to deal with conditions promoted by dihydrotestosterone (DHT), a powerful hormone the body produces from testosterone. DHT-induced conditions consist of androgenic alopecia (male pattern hair loss), benign prostatic hyperplasia (enlarged prostate) and prostate cancer.

How Does This Hair Loss Medication Work

In individuals genetically predisposed to male pattern baldness, DHT binds to receptors in hair roots at the top of the scalp. Hair roots on the back and side of the head are genetically resistant to DHT, which discusses the typical pattern seen in male baldness.
With Propecia, the active component finasteride triggers a fast decrease in DHT concentration to fight male pattern hair loss. Within 1 Day of taking Propecia, the concentration of DHT can lower to 65 percent. The complete results of Propecia can take 3 months or more to appear.

 

Propecia Side Effects

The most typical adverse effects connected with Propecia consist of:

  • Decreased Sex Drive
  • Impotence
  • Premature Ejaculation

The most regularly reported negative responses to this hair loss drug relates to sexual health dysfunctions. A U.S. Fda (FDA) evaluation of the results of taking this drug on patients exposed a vast array of sexual negative effects in otherwise healthy Propecia users ages 21 to 46. These issues continued for approximately 40 months after the cessation of treatment.
Negative sexual dysfunctions were more prevalent in more youthful males. A number of negative effects have actually been discovered to enhance or return to normal when Propecia treatment is stopped, while others might remain to influence the client for a number of months and even years. In severe instances, sexual function was damaged for the long term with irreversible consequences.

Some Other Common Side Effects of Propecia consist of:

  • Allergy breakouts, itching, hives and swelling of the face and lips
  • Tenderness and swelling of the Breasts
  • Testicular discomfort
  • Male infertility or low sperm count
  • Male Breast Cancer
  • Poor Mood/Depression

It deserves pointing out that no clear linkage between Propecia use and  negative sexual effects. The drug’s methodology, nevertheless, makes the connection extremely probable. Finasteride, the active component in Propecia, reduces the body’s level of DHT, an androgen hormone that plays a significant function in sexuality and sexual development.




Link To Prostate Cancer

The FDA launched a security statement during the month of June in 2011 cautioning that Propecia and other 5-alpha-reductase inhibitors might enhance the likelihood of a severe type of prostate cancer. Referred to as high grade prostate cancer, this is the most fatal kind.

This is extremely aggressive and proliferates rapidly, commonly infecting other locations like the lymph nodes and bones. These cancer cells are big, tough to deal with and re-emerge more often than lower graded prostate cancers.
As the cancer threat appears to be low with Proscar, the FDA dispersed the statement to notify medical professionals and clients of safety modifications to the caution and precaution labeling for this course of drugs. Proof of the associated risks from this course of drugs originates from 2 big scientific trials:

i)PCPT the 7 year Prostate Cancer Prevention Trial

ii)DECREASE the 4 year Decrease by Dutasteride of Prostate Cancer Occasions trial.
If finasteride might be utilized to reduce the threat of prostate cancer, both trials looked  to figure out if it worked. While PCPT and DECREASE worked well in lowering occurrences of low grade kinds of prostate cancer, clients in both trials were discovered to be at a higher danger of developing high grade prostate cancers.

Actions By The FDA

When professional trial results contravened Merck’s initial assertion that the sexual negative effects of Propecia would stop when treatment ends, the FDA modified the drug’s warning label appropriately.

In 2011, the FDA included that some negative effects, such as impotence, might continue after the drug has been stopped. A few months later, the FDA made another modification, stating that some clients experienced adverse sexual effects long after the drug had been stopped indefinitely.

Adverse effects provided by the FDA consist of:

  • Sex drive disorders
  • Ejaculation dysfunctions
  • Infertility
  • Inability To Climax
  • Low Sperm Count

Before arriving at this statement, the FDA evaluated 421 survey reports of sexual negative effects reported to its side effects database from 1998 to 2011. A total amount of 59 cases  revealed sexual disorders that continued for a minimum of 3 months after Propecia use ended, with adverse conditions consisting of impotence, reduced sexual libido, ejaculation problems and orgasm conditions.

Proscar A Damaging Drug?

Proscar, like Propecia, contains the active component finasteride. Widely used in medicine to deal with an enlarged prostate and assist in normalizing associated urinary tract conditions, Proscar consists of 5 times the amount of finasteride that was used in Propecia and provides a comparable variety of prospective negative effects.

A PLESS study conducted over a 4 year period (Proscar Long Term Efficacy and Safety Study), utilized over 3 thousand 45-78 year old males who had benign prostatic hyperplasia (enlarged prostate), had noticeable results.

Of those involved 3.7% that were treated with Proscar had to stop treatment after experiencing these same side effects. Another similar study concluded with 4 out of 1500 patients developing breast cancer. 200% higher than the rate of breast cancer among average males



Civil Court Cases Against Propecia

The negative side effects of taking Propecia was limited to a small percentage of users. Nevertheless, these issues caused extreme psychological upset to a number of users. long term sexual disorders, was an extreme price to pay for this course of drugs.
Numerours law suits have been filed against Merck, declaring the company omitted was negligent in not disclosing data about indefinite negative impacts of taking Propecia on the product labelling.  To date over 250 court cases have been brought against Merck.

 

Hair Loss Treatment Options

You have the following options when it comes to finding the best hair loss treatment:
  • Accept it Gracefully
  • Use Drugs and run the risk of long term side effects
  • Adorn a wig or hairpiece
  • Try Extenstions
  • Have hair replacement therapy
  • Use a natural treatment hair tonic spray like Provillus

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Hair Loss Treatment Prices

The cost of hair loss treatment can vary according to what means you opt for. You can pay thousands for hair transplant surgery especially if you have to go back every few months to get more done. Wigs  can cost anywhere from $50 to $5000 and up. But it all depends on getting something that looks good.

Hair extensions can range from $40-$500, but these may not be applicable for all individuals. Plus they can even put more stress on the existing receding hairline, and like a hairpiece or toupee they don’t actually tackle the root of the problem.

Hair loss treatment Without Surgery

You can opt for a less severe form of treatment that only involves applying a tonic lotion like Provillus to your hair.  The side effects of it are quite mild, usually only reduced to mild itching or a redness on the scalp, if any at all. You can read the full review of it on our homepage plus there is a unique formula for men, and another separate formula for women. Users have been experiencing some great results with it.




If you are worried about cost, you can order a risk free trial of Provillus and after that it costs about $30 for a months supply. Results can take up to 4 months to mature.

 

 

 

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